Age-related Changes in Bending Fatigue of Human Cortical Bone
نویسنده
چکیده
Age-related non-traumatic fractures are a major health problem. Historically, only bone mass was considered to predict fracture risk but other factors, including accumulation of microdamage, may also affect bone quality and contribute to bone fragility. Previous studies conducted in our laboratory have demonstrated that the predisposition of bone to form linear microcracks and not diffuse damage is a significant contributor to bone fragility [1]. It is, therefore, likely that an age-related increase in bone fragility could be caused by an alteration in mode and magnitude of microdamage formation.
منابع مشابه
The effects of testing methods on the flexural fatigue life of human cortical bone.
A flexural model of four-point bending fatigue that has been experimentally validated for human cortical bone under load control was used to determine how load and displacement control testing affects the fatigue behavior of human cortical bone in three-point and symmetric four-point bending. Under load control, it was predicted that three-point bending produced no significant differences in fa...
متن کاملAge-related change in the damage morphology of human cortical bone and its role in bone fragility.
Application of cyclic loading results in the formation of distinct strain-dependent microdamage morphologies. It is still unknown; however, how the morphology of microdamage affects age-related increase in bone fragility. In this study, four-point bending fatigue tests were conducted on aging human bone (age 26 to 89) in conjunction with histological evaluation of the resultant tensile (diffuse...
متن کاملP29: Changes in Thickness and Intelligence
Neuroimaging research indicates that human intellectual ability is associated to brain structure including the thickness of the cerebral cortex. Most studies show that general intelligence is positively associated with cortical thickness in areas of association cortex allocated throughout both brain hemispheres. Changes in cortical thickness over time have been related to intelligence, but whet...
متن کاملA comparison of the fatigue behavior of human trabecular and cortical bone tissue.
The fatigue properties of trabecular bone tissue (single trabeculae) and similarly sized cortical bone specimens from human tibia were experimentally determined on a microstructural level using four-point bending cyclic tests, and they were compared based on modulus, mineral density, and microstructural characteristics. The results showed that trabecular specimens had significantly lower moduli...
متن کاملValidation of speed of sound for the assessment of cortical bone maturity.
Bone changes its structural and physical properties during maturation. In order to validate ultrasound measurements with regard to their usefulness in assessing cortical bone maturation, speed of sound (SOS) data were compared with mechanical properties (elastic modulus, bending strength, and cortical surface hardness), density and water content. Thirty pig mandibles were selected from three di...
متن کامل